Last Update April 6, 2011

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Peroxisomes belong to the microbody family, a class of ubiquitous and essential cell organelles. Fatty acid beta-oxidation is a general feature of peroxisomes, but in higher eukaryotes, they have a number of functions not shared by peroxisomes in lower eukaryotes, including ether phospholipid biosynthesis, fatty acid alpha-oxidation and glyoxylate detoxification. Peroxisomal disorders are a group of inherited diseases that are usually classified in two groups; Peroxisome Biogenesis Disorders (PBDs) and single Peroxisomal Enzyme Deficiencies (PEDs). Peroxisomes play an indispensable role in human physiology, as can be concluded from the devastating consequences of a deficiency of peroxisomes as observed in Zellweger patients.


Peroxisome-related nanopublications from Peroxisome Knowledge Base coming soon.